Acetyl Glutamine

Acetyl Glutamine is an acetylated form of the amino acid glutamine, used in cosmetics as a water-binding humectant. It attracts moisture and promotes a supple feel, complementing barrier-care formulas, though evidence for it is limited.
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Snapshot

Overview
A moisture-binding amino acid that leaves skin feeling quenched.
Category
Hydration, Barrier Support, Skin Conditioning
Type
Humectant

Ratings

Overall Rating

Fair

Comedogenic Risk

None

Not typically evaluated for comedogenicity — no standardized rating available.

Is Acetyl Glutamine a Good Ingredient?

This rates Fair: Acts as a humectant with preliminary support, so hydration gains are likely modest and formula-dependent. Risk: may trigger mild irritation in sensitive skin.

Skin Benefits

Helps skin feel quenched and comfortable, lending a fresher, cushioned look. Evidence is preliminary, so outcomes may be modest.

Uses in Skincare & Cosmetics

Common in hydrating serums, toners, and gel moisturizers designed for daily moisture support and resilience against dryness.

Safety

Generally considered low risk in leave-on products, but patch testing is advisable for reactive skin. No specific regulatory limits are commonly cited.