Acetyl Glutamine is an acetylated form of the amino acid glutamine, used in cosmetics as a water-binding humectant. It attracts moisture and promotes a supple feel, complementing barrier-care formulas, though evidence for it is limited.
A moisture-binding amino acid that leaves skin feeling quenched.
Category
Hydration, Barrier Support, Skin Conditioning
Type
Humectant
Ratings
Overall Rating
Fair
Comedogenic Risk
None
Not typically evaluated for comedogenicity — no standardized rating available.
Our take
Is Acetyl Glutamine a Good Ingredient?
This rates Fair: Acts as a humectant with preliminary support, so hydration gains are likely modest and formula-dependent. Risk: may trigger mild irritation in sensitive skin.
What it does
Skin Benefits
Helps skin feel quenched and comfortable, lending a fresher, cushioned look. Evidence is preliminary, so outcomes may be modest.
Where you'll find it
Uses in Skincare & Cosmetics
Common in hydrating serums, toners, and gel moisturizers designed for daily moisture support and resilience against dryness.
Before you use it
Safety
Generally considered low risk in leave-on products, but patch testing is advisable for reactive skin. No specific regulatory limits are commonly cited.