Acetyl Octapeptide-3 is a synthetic eight-amino-acid peptide, often listed as SNAP-8 in cosmetics. Serums and creams use it to reduce the appearance of expression lines, though independent evidence is limited.
Known as SNAP-8, it may soften the look of expression lines.
Category
Anti-aging, Tone/Texture, Firming
Type
Peptide
Ratings
Overall Rating
Fair
Comedogenic Risk
None
Not typically evaluated for comedogenicity — no standardized rating available.
Our take
Is Acetyl Octapeptide-3 a Good Ingredient?
This lands at Fair because most support comes from supplier data and small studies, so results tend to be mild and short-lived. A small risk of irritation exists, especially near the eye area or at higher use levels.
What it does
Skin Benefits
May soften the look of forehead and smile lines for a temporarily smoother appearance. Available data is preliminary, so effects are usually modest.
Where you'll find it
Uses in Skincare & Cosmetics
Included in lightweight serums, gel creams, and primer-style treatments that blur lines under makeup. Often paired with humectants or film-formers in leave-on formulas.
Before you use it
Safety
Generally well tolerated, but sensitive skin may experience transient redness or stinging; patch testing is prudent. No widely recognized regulatory restrictions at typical cosmetic levels.