Acetyl Tetrapeptide-9

Acetyl Tetrapeptide-9 is a synthetic four-amino-acid peptide developed for topical skincare. Brands add it to firming and texture products to refine the look of skin structure, though supporting studies remain limited.
Like this ingredient?

Snapshot

Overview
A peptide meant to smooth skin and improve firmness over time.
Category
Firming, Anti-aging, Tone/Texture
Type
Peptide

Ratings

Overall Rating

Fair

Comedogenic Risk

None

Not typically evaluated for comedogenicity — no standardized rating available.

Is Acetyl Tetrapeptide-9 a Good Ingredient?

This lands at Fair due to scarce independent clinical support; perceived firming and smoothing are usually modest. A minor risk of irritation or sensitization is possible, particularly for sensitive skin.

Skin Benefits

May smooth skin’s surface and improve the look of density and firmness over time. Evidence is modest, so visible changes are typically gradual.

Uses in Skincare & Cosmetics

Used in renewal essences, night creams, and treatment boosters targeting texture refinement and firmness. Sometimes included in concentrated ampoules for specific areas.

Safety

Typically low irritation potential, but patch testing is advisable for reactive skin due to possible redness or itching. No common regulatory restrictions are noted for standard cosmetic use.