Our take
Is Glyoxal a Good Ingredient?
It rates Poor because, despite working as a preservative and crosslinker, its reactive dialdehyde chemistry carries a comparatively high risk of irritation and sensitization. The benefit-to-risk balance simply doesn't hold up against safer preservative alternatives, which is why it sits at the bottom.
What it does
Skin Benefits
Helps keep products fresher by discouraging microbe growth and can improve formula durability. Those with reactive skin may prefer to avoid it.
Where you'll find it
Uses in Skincare & Cosmetics
Used in certain water-based gels, lotions, and nail products to stabilize texture and extend shelf life.
Before you use it
Strong skin sensitizer and irritant. Restricted in many jurisdictions; avoid use in most leave-on skin products. If used in nail products, follow strict concentration limits and avoid skin contact; keep away from eyes and broken skin.