Histidine

Histidine is an essential amino acid that also works as a water-soluble humectant in skin and hair formulas. It draws in moisture and helps buffer formula pH, which supports both hydration feel and product stability.
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Snapshot

Overview
An amino acid that draws moisture to skin and keeps formulas gentle.
Category
Hydration, Skin Conditioning
Type
Humectant

Ratings

Overall Rating

Good

Comedogenic Risk

None

Not typically evaluated for comedogenicity — no standardized rating available.

Is Histidine a Good Ingredient?

It's Good because it's a gentle humectant and pH buffer that reliably supports hydration and formula comfort, though evidence for standout skin effects beyond moisturization is limited, which is what keeps it from Great.

Skin Benefits

Boosts surface hydration for softer, more comfortable skin. Its buffering action can help keep formulas feeling gentle on application.

Uses in Skincare & Cosmetics

Often included in hydrating toners, essences, and lightweight serums to improve moisture retention and sensorial comfort.

Safety

Generally well tolerated with low irritation potential for most skin types. No major cosmetic regulatory restrictions noted.