Palmitoyl Tetrapeptide-94

Palmitoyl Tetrapeptide-94 is a lipidated tetrapeptide developed for cosmetic products. It's used for general skin conditioning and surface texture refinement, though published evidence and real-world data are still limited.
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Snapshot

Overview
A peptide meant to smooth skin texture, though evidence is limited.
Category
Skin Conditioning, Tone/Texture
Type
Peptide

Ratings

Overall Rating

Fair

Comedogenic Risk

None

Not typically evaluated for comedogenicity — no standardized rating available.

Is Palmitoyl Tetrapeptide-94 a Good Ingredient?

Rated Fair due to limited independent clinical evidence, so benefits may be modest and inconsistent. There's also a minor risk of irritation in sensitive users, which together keep it below Good.

Skin Benefits

Early evidence suggests it may improve skin feel and the look of uneven texture, but strong clinical data are limited. Best considered a supportive peptide rather than a primary results driver.

Uses in Skincare & Cosmetics

Used in essences, boosters, and moisturizers to complement established actives in a routine.

Safety

Expected to be generally tolerable, but patch testing is advisable due to sparse real-world data. Mild redness or stinging can occur in reactive skin. No specific regulatory restrictions are commonly cited.