Palmitoyl Tetrapeptide-94 is a lipidated tetrapeptide developed for cosmetic products. It's used for general skin conditioning and surface texture refinement, though published evidence and real-world data are still limited.
A peptide meant to smooth skin texture, though evidence is limited.
Category
Skin Conditioning, Tone/Texture
Type
Peptide
Ratings
Overall Rating
Fair
Comedogenic Risk
None
Not typically evaluated for comedogenicity — no standardized rating available.
Our take
Is Palmitoyl Tetrapeptide-94 a Good Ingredient?
Rated Fair due to limited independent clinical evidence, so benefits may be modest and inconsistent. There's also a minor risk of irritation in sensitive users, which together keep it below Good.
What it does
Skin Benefits
Early evidence suggests it may improve skin feel and the look of uneven texture, but strong clinical data are limited. Best considered a supportive peptide rather than a primary results driver.
Where you'll find it
Uses in Skincare & Cosmetics
Used in essences, boosters, and moisturizers to complement established actives in a routine.
Before you use it
Safety
Expected to be generally tolerable, but patch testing is advisable due to sparse real-world data. Mild redness or stinging can occur in reactive skin. No specific regulatory restrictions are commonly cited.