Pentapeptide-4

Pentapeptide-4 is a short, water-soluble peptide made of five amino acids used in cosmetic formulations. It's included to support goals like smoother texture and a more refined look, though evidence for specific performance is limited.
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Snapshot

Overview
A peptide meant to make skin's surface look smoother and more even.
Category
Tone/Texture, Skin Conditioning
Type
Peptide

Ratings

Overall Rating

Fair

Comedogenic Risk

None

Not typically evaluated for comedogenicity — no standardized rating available.

Is Pentapeptide-4 a Good Ingredient?

Rated Fair because the clinical support for visible texture improvement is limited, so results can be modest or variable. There's also a small risk of irritation or sensitization for some users, especially in leave-on formulas, which keeps it below Good.

Skin Benefits

May promote a more even-looking skin surface and a softer appearance of roughness; available data is limited, so outcomes can vary. Offers a lightweight way to complement texture-smoothing routines.

Uses in Skincare & Cosmetics

Included in serums, essences, and daily moisturizers designed for texture refinement in non-invasive skincare regimens.

Safety

Generally considered low risk at cosmetic use levels, but mild irritation or sensitization can occur, particularly on sensitive skin. Patch testing is advisable for first-time users. No widely noted regulatory restrictions for typical skincare use.