Snapshot
- Overview
- An enzyme that breaks down buildup to smooth and refine skin texture.
- Category
- Exfoliating, Tone/Texture
- Type
- Exfoliant
Protease
Protease is a protein-cleaving enzyme derived from microbes, plants, or fermentation for topical use. It's included in exfoliating formulas to loosen surface buildup and refine texture, though performance is pH-dependent and human cosmetic evidence is limited.
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Our take
Is Protease a Good Ingredient?
It rates Fair: it can help surface exfoliation, but benefits depend on pH and enzyme activity, and evidence for lasting results is limited; misuse or high activity may irritate or disrupt the barrier.
What it does
Skin Benefits
Helps smooth the skin’s surface by dissolving buildup of dead proteins, revealing a more refined look; results can vary with pH and formula. Evidence for long-term skin improvements is limited.
Where you'll find it
Uses in Skincare & Cosmetics
Found in exfoliating cleansers, peel gels, and wash-off masks designed for gentle resurfacing. Occasionally included in serums or toners formulated for enzyme-based renewal.
Before you use it
Safety
Irritation or stinging can occur, especially at lower pH, higher activity, or with overuse; patch test and avoid broken or compromised skin. Use alongside moisturizers and limit frequency if sensitivity appears.
Products with Protease
