Sh-Octapeptide-4

Sh-Octapeptide-4 is a biotechnology-produced peptide of eight amino acids patterned after a human peptide. Included in formulas aimed at improving the appearance of smoothness and firmness, and for skin conditioning; topical evidence remains limited.
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Snapshot

Overview
A lab-made peptide aimed at softening lines and boosting firmness.
Category
Anti-aging, Firming, Tone/Texture, Skin Conditioning
Type
Peptide

Ratings

Overall Rating

Fair

Comedogenic Risk

None

Not typically evaluated for comedogenicity — no standardized rating available.

Is Sh-Octapeptide-4 a Good Ingredient?

Fair, because although it's proposed to improve smoothness and elasticity, strong clinical data are scarce and effects may be subtle. A small risk of sensitivity also exists for some users.

Skin Benefits

May soften the look of fine lines and support the appearance of elasticity, though evidence for notable outcomes is still limited. Contributes to a more refined, well-moisturized feel.

Uses in Skincare & Cosmetics

Included in facial serums, creams, and sheet masks designed for rejuvenating care.

Safety

Typically well tolerated with low irritation likelihood; stop use if discomfort or redness develops. No known cosmetic regulatory restrictions specific to this peptide.