Sh-Oligopeptide-1 is a biotechnology-derived, water-soluble peptide modeled on human signaling fragments. It's used in serums and creams to refine skin feel, promote a smoother look, and support formulas targeting a youthful-looking finish.
Not typically evaluated for comedogenicity — no standardized rating available.
Our take
Is Sh-Oligopeptide-1 a Good Ingredient?
Good, because as a growth factor peptide commonly used in anti-aging skincare, it has a plausible mechanism for supporting skin renewal and smoothing the look of fine lines. The supporting research is still developing rather than extensive, which is why it lands at Good rather than Great.
What it does
Skin Benefits
Helps soften the look of fine lines and supports a bouncier appearance, though evidence for strong, long-term effects is limited.
Where you'll find it
Uses in Skincare & Cosmetics
Found in lightweight serums, ampoules, and eye creams, often layered beneath moisturizers, and also appears in sheet masks for a short-term cosmetic boost.
Before you use it
Safety
Generally considered well tolerated in leave-on products, with a low but real chance of mild irritation or redness; patch testing is advisable. Avoid applying to compromised skin. No specific regulatory restrictions are widely recognized for this peptide in cosmetics.