Sh-Oligopeptide-2 is a synthesized, human-sequence-inspired oligopeptide created via biotechnology for cosmetic use. Brands include it in leave-on products to improve surface suppleness and support even-looking tone in appearance-focused routines.
Not typically evaluated for comedogenicity — no standardized rating available.
Our take
Is Sh-Oligopeptide-2 a Good Ingredient?
Good, because as a bioengineered growth factor peptide it plausibly supports skin repair and improves overall skin appearance, and it's a regular feature in premium anti-aging products. It stays at Good rather than Great since the supporting data is preliminary.
What it does
Skin Benefits
May improve the look of elasticity and promote a more uniform complexion, though available data is preliminary, so results can vary.
Where you'll find it
Uses in Skincare & Cosmetics
Common in gel serums and daily moisturizers targeting balanced tone. Sometimes included in brightening eye gels or focused spot treatments.
Before you use it
Safety
Typically low irritation potential, but monitor for stinging or redness, especially in concentrated serums. Use cautiously near the eye area and discontinue if sensitivity occurs. No well-established regulatory limits noted.