Snapshot
- Overview
- A bioengineered peptide that conditions skin and softens texture.
- Category
- Skin Conditioning, Anti-aging, Tone/Texture
- Type
- Peptide
Sh-Polypeptide-22
Sh-Polypeptide-22 is a bioengineered, water-soluble cosmetic polypeptide made via recombinant methods. It's used for skin conditioning and to smooth visible texture; support is modest and outcomes depend on dose and formulation.
Like this ingredient?
Our take
Is Sh-Polypeptide-22 a Good Ingredient?
It lands at Fair because the evidence for visible smoothing from this recombinant peptide is modest and depends heavily on formulation and dose, so results aren't consistent enough to rate higher. Peptide actives like this one also carry a small risk of irritation or sensitization.
What it does
Skin Benefits
With routine use it may soften the look of fine lines and add suppleness, though any improvement tends to be modest and depends heavily on the rest of the formula.
Where you'll find it
Uses in Skincare & Cosmetics
It appears in anti-aging serums and eye creams, and sometimes in concentrated ampoules for nighttime routines.
Before you use it
Safety
It's water-soluble and generally well tolerated, with a low chance of clogging pores or causing photosensitivity. Patch test if your skin tends to react, and stop use if redness or itching shows up.
