Sodium RNA is the water-soluble sodium salt of ribonucleic acid made via biotechnological processing. It's used to support moisture balance and improve formula slip; evidence for distinct skin effects is limited, so its function is largely auxiliary.
An RNA-derived ingredient that helps skin hold onto moisture.
Category
Hydration, Skin Conditioning
Type
Humectant
Ratings
Overall Rating
Fair
Comedogenic Risk
None
Not typically evaluated for comedogenicity — no standardized rating available.
Our take
Is Sodium RNA a Good Ingredient?
It rates Fair: it provides basic humectancy but has limited clinical evidence for distinct skin benefits beyond supporting hydration, so its impact stays modest. Minor irritation is uncommon but possible, especially in very reactive skin.
What it does
Skin Benefits
It helps skin retain water for a plumper, smoother feel, though evidence for broader rejuvenating effects is limited. It can improve the comfort of hydrating formulas.
Where you'll find it
Uses in Skincare & Cosmetics
It's included in serums, gels, and hydrating toners to support water-binding systems, and used in moisturizers to complement humectants like glycerin or hyaluronic acid.
Before you use it
Safety
It's generally considered low risk at typical levels and unlikely to clog pores. Mild stinging or sensitivity can occur on compromised skin; discontinue if irritation appears. No specific cosmetic-use restrictions are widely cited.