Tetrapeptide-14

Tetrapeptide-14 is a synthetic four-residue peptide optimized for water-based, leave-on skincare. It's selected for comfort-focused, sensitive-skin routines and general conditioning in light serums or gels, but strong independent support is still limited.
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Snapshot

Overview
A peptide formulated to comfort sensitive, reactive-feeling skin.
Category
Soothing, Sensitive Skin, Skin Conditioning
Type
Peptide

Ratings

Overall Rating

Fair

Comedogenic Risk

None

Not typically evaluated for comedogenicity — no standardized rating available.

Is Tetrapeptide-14 a Good Ingredient?

It's Fair because soothing and anti-redness claims lack solid independent clinical backing, even though the peptide is formulated to be gentle. Even calming peptides like this one can occasionally trigger sensitivity.

Skin Benefits

Targets visible redness and signs of discomfort in reactive skin. Independent evidence remains limited.

Uses in Skincare & Cosmetics

Common in calming serums, lightweight moisturizers, and post-procedure sheet masks for easily irritated skin.

Safety

Usually well tolerated and suitable for sensitive-skin products, but patch testing is advisable if you're reactive. No commonly recognized cosmetic regulatory restrictions.